Fooly Cooly
Naota Nanadaba is just an ordinary boy, with an ordinary life, with ordinary people around him, living in an ordinary town... or at least he wishes that were all true! Between his eccentric father and unconventional grandfather and putting up with the advances of his older brother's teenage ex-girlfriend Mamimi, Naota isn't leading a boring life at all! To make matters worse, a pink-haired, and apparently totally insane, girl named Haruko Haruhara shows up and turns Naota's life completely upside down!! What does Haruko want from Naota? And, why is he suddenly growing a large horn on his head?!
Aired 26/04/2000EP 1 - Fooly Cooly

FLCL
Naota is a detached sixth grader afflicted by the pangs of puberty. He's fooling around with his brother's ex-girlfriend when a crazed girl on a motor scooter runs him over, brains him with a bass guitar, and moves into his house. This pink-haired girl, Haruko - who claims she's an alien - hurls Naota into the middle of a mega-corporation's secret agenda. Oh, and now giant battling robots shoot from his skull. Mix in mind-bending animation and tunes that echo through your cerebellum to top off the trip that will have you falling hard for FLCL.
(Source: Funimation)