From the Edge of Night
A man sits alone in his study surrounded by scrawlings and mumbling about a forthcoming apocalypse as we see a photo of a group of ageless young albinos called the Befort Children. We switch focus several times as we follow the Children throughout history - in Holland, where their attempts to convince a young boy called Conrad to join them fail after they send him a postcard depicting a strange image, to Sweden at the turn of the century, and to the South Eastern Islands where they arrive too late at the bedside of a dead woman named Serafine who has been painting the same image as on the postcard. Strangely, one of the Children, Mel suffers amnesia and panics, getting captured by the strange young man Duma and his cronies while the other Children escape. Fast-forward to 2012 in the Islands, and the roguish Toma practices his martial arts before discovering a young girl, Helga, lying on a statue silently. He visits his mother, a bogus fortune teller, and helps a young thief, Chit, escape his pursuers, before returning home to see Helga being taken away by some mysterious men...
Aired 05/10/2004EP 1 - From the Edge of Night

Fantastic Children
A group of enigmatic white-haired children has been spotted at different times and places in Europe for over 500 years. Always with the appearance of 11-year-olds, they behave far more mature than they should be, never grow old, and seem to have supernatural power. What they have been seeking is a girl, and the only clue they have is a picture with a crescent moon. Now, in the year of 2012, an athletic boy named Tohma is about to be involved in this centuries-long mystery.
(Source: Anime News Network)