The Northern Wall of Briggs
Still on Scar’s trail, Kimblee figures out that he headed north and follows him there. When Kimblee gets word that Scar and Marcoh are on a train, he boards it by having another train run alongside it, but instead of finding Marcoh, he finds Yoki there. Kimblee is then attacked by Scar, and the two recognize each other from their previous encounter years ago. Before Kimblee can really do anything, Scar impales him with a metal pipe, and this leaves Kimblee no choice but to use his alchemy to separate the two parts of the train, with Scar on the other part. Realizing that something happened, the train’s operators stop it and find the injured Kimblee, but he orders them to keep going. Unbeknownst to Kimblee, the real Marcoh is heading north on foot with May Chang. The two eventually reach the shack where Scar’s brother’s research is located, and they find it intact.
Aired 22/11/2009EP 33 - The Northern Wall of Briggs

Fullmetal Alchemist: Brotherhood
"In order for something to be obtained, something of equal value must be lost."
Alchemy is bound by this Law of Equivalent Exchange—something the young brothers Edward and Alphonse Elric only realize after attempting human transmutation: the one forbidden act of alchemy. They pay a terrible price for their transgression—Edward loses his left leg, Alphonse his physical body. It is only by the desperate sacrifice of Edward's right arm that he is able to affix Alphonse's soul to a suit of armor. Devastated and alone, it is the hope that they would both eventually return to their original bodies that gives Edward the inspiration to obtain metal limbs called "automail" and become a state alchemist, the Fullmetal Alchemist.
Three years of searching later, the brothers seek the Philosopher's Stone, a mythical relic that allows an alchemist to overcome the Law of Equivalent Exchange. Even with military allies Colonel Roy Mustang, Lieutenant Riza Hawkeye, and Lieutenant Colonel Maes Hughes on their side, the brothers find themselves caught up in a nationwide conspiracy that leads them not only to the true nature of the elusive Philosopher's Stone, but their country's murky history as well. In between finding a serial killer and racing against time, Edward and Alphonse must ask themselves if what they are doing will make them human again... or take away their humanity.
(Source: MAL Rewrite)