The Evil Spirit
Jotaro learns the secret of his Stand power and about his family's enemy, the vampire DIO. Later, Jotaro is attacked by Noriaki Kakyoin and his Stand Hierophant Green, an assassin controlled by DIO. When Holly falls into a Stand-induced coma, Joseph, Jotaro, and the others embark on a dangerous journey to Egypt to save her life and end the 100-year battle between DIO and the Joestar family.
Aired 25/05/2000EP 1 - The Evil Spirit

JoJo's Bizarre Adventure (2000)
Kujo Jotaro is a normal, popular Japanese high-schooler, until he thinks that he is possessed by a spirit, and locks himself in prison. After seeing his grandfather, Joseph Joestar, and fighting Joseph's friend Muhammad Abdul, Jotaro learns that the "Spirit" is actually Star Platinum, his Stand, or fighting energy given a semi-solid form. Later, his mother gains a Stand, and becomes sick. Jotaro learns that it is because the vampire Dio Brando has been revived 100 years after his defeat to Jonathan Joestar, Jotaro's great-great-grandfather. Jotaro decides to join Joseph and Abdul in a trip to Egypt to defeat Dio once and for all.